While the mystery isn't as good as Lost's, if you like the sci-fi aspects of Lost (like most people that got incredibly disappointed with the show and stopped watching) The Lost Room was a great mini-series on Sci-fi.
I REALLY liked the Sci-fi remake of Battlestar Galactica and Stargate SG1, Atlantis, and Universe are some of the best Sci-fi that was/is on television. Also, Farscape is AMAZINGLY good (and one of the reasons why SG1 was even more incredible for me). Claudia Black is an incredible actress (and definitely very pleasing to the eyes as well).
Besides the above, the only TV I watch is: House, The Big Bang Theory, How I Met Your Mother, Two and a Half Men, Grey's Anatomy (guilty pleasure), Mythbusters, Man vs Food, and Boondocks (INCREDIBLY funny shit).
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